Azathioprine EP Impurity D CAS 6339-54-4
| CAS No. | 6339-54-4 |
| Molecular Formula | C4H5N3O2S |
| Molecular Weight | 159.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Azathioprine EP Impurity D (CAS 6339-54-4), a pharmacopoeial impurity reference standard (molecular formula C4H5N3O2S, MW 159.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, Azathioprine EP Impurity D is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 159.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H5N3O2S |
| Molecular Weight | 159.17 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Azathioprine Standards
- Azathioprine EP Impurity C (CAS 4897-25-0)
- Azathioprine Impurity 9 (CAS 1190008-04-8)
- Azathioprine EP Impurity B (CAS 157930-13-7)
- Azathioprine EP Impurity B (CAS 50-44-2)
- Azathioprine Impurity 21 (CAS 30467-02-8)
- Azathioprine Impurity 8 (CAS 50-66-8)
- Azathioprine Impurity 6 (CAS 154-42-7)
- Azathioprine Impurity 12 (CAS 1192-53-6)
Recommended Standards
- Ribavirin Impurity 56 (CAS CATO-C4X-141356)
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- Ceftriaxone Impurity 48 (CAS CATO-C4X-116348)
- 3-Hydroxy-5-phenylpyrrole (CAS 100750-40-1)
- Netupitant Impurity 10 (CAS CATO-C4X-122310)
- Oxybuprocaine Impurity 4 (CAS 1096863-52-3)
- Dotinurad Impurity 226 (CAS CATO-C4X-2494226)
- N-(6-(tert-Butyl)-5-cyclopropoxypyridin-3-yl)methanesulfonamide (CAS 1243445-50-2)
- (2-Methylbenzo[d][1,3]dioxol-5-yl)methanol (CAS 71203-54-8)
- (S)-2-Nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-ol (CAS 187235-08-1)
- 3-[(Dimethylamino)methyl]-4-hydroxybenzaldehyde (CAS 116546-04-4)
- 3-Oxo-4-(4-chlorophenyl)butanoyl chloride (CAS 1987320-77-3)
- Cyclohexyltriethoxysilane (CAS 18151-84-3)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com