Troxipide Impurity 20 CAS 4997-88-0
| CAS No. | 4997-88-0 |
| Molecular Formula | C15H16N2O4 |
| Molecular Weight | 288.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Troxipide Impurity 20 (C15H16N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Troxipide Impurity 20 (CAS 4997-88-0) is a certified pharmaceutical impurity reference standard with the molecular formula C15H16N2O4 and a molecular weight of 288.30 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H16N2O4 |
| Molecular Weight | 288.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Troxipide Standards
Recommended Standards
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- Ceftolozane Impurity 38 (CAS CATO-C4X-240638)
- Ceftiofur Impurity 21 (CAS CATO-C4X-158121)
- Pyrantel EP impurity A (CAS 36700-38-6)
- Drospirenone EP Impurity G (CAS 932388-90-4)
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- Methyl 2-chloro-4-(difluoromethoxy)benzoate (CAS 97914-56-2)
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- N-allyl-2-(N-phenylphenylsulfonamido)acetamide (CAS 339103-00-3)
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