tert-Butyl (4-cyano-1H-imidazol-5-yl)carbamate CAS 500024-61-3
| CAS No. | 500024-61-3 |
| Molecular Formula | C9H12N4O2 |
| Molecular Weight | 208.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-Butyl (4-cyano-1H-imidazol-5-yl)carbamate (CAS 500024-61-3) is a high-purity analytical reference standard with the molecular formula C9H12N4O2 and a molecular weight of 208.22 g/mol.
The molecular framework of tert-Butyl (4-cyano-1H-imidazol-5-yl)carbamate (C9H12N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12N4O2 |
| Molecular Weight | 208.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 4 |
Recommended Standards
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- 2-(Thiazol-5-yl)propan-2-ol (CAS 1451737-08-8)
- 2-Amino-3-methyl-N-(3-pyridinylmethyl)butanamidehydrochloride (CAS 1236257-03-6)
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- Erlotinib Impurity 83 (CAS CATO-C4X-106983)
- Ethyl (1S,2R)-2-(cbz-Amino)cyclopentanecarboxylate (CAS 1140972-32-2)
- 3-Formyl-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 221323-58-6)
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