5,7-Difluoro-3-iodo-1-(phenylsulfonyl)-1H-indole CAS 500139-01-5
| CAS No. | 500139-01-5 |
| Molecular Formula | C14H8F2INO2S |
| Molecular Weight | 419.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5,7-Difluoro-3-iodo-1-(phenylsulfonyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5,7-Difluoro-3-iodo-1-(phenylsulfonyl)-1H-indole (CAS 500139-01-5), a certified reference material (molecular formula C14H8F2INO2S, MW 419.19 g/mol) for analytical method development and quality control.
The molecular framework of 5,7-Difluoro-3-iodo-1-(phenylsulfonyl)-1H-indole (C14H8F2INO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H8F2INO2S |
| Molecular Weight | 419.19 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoro Standards
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Recommended Standards
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- 1-{3-[(2,2,3,3,4,4,5,5-octafluoropentyl)oxy]-5-(trifluoromethyl)pyridin-2-yl}ethan-1-one (CAS 882747-43-5)
- 8-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-1,2,3,4-tetrahydroquinoxaline-2,3-dione (CAS 341966-42-5)
- 3-(4-Methoxyphenyl)-1-oxa-2,4,8-triazaspiro[4.5]dec-2-ene (CAS 37143-33-2)
- 4-Chlorophenylboronic acid (CAS 1679-18-1)
- 2-(1-Ethyl-1h-imidazol-5-yl)cyclopropane-1-carboxylic acid (CAS 1488139-72-5)
- Benzyl cyclohexyl hydrogen phosphate (CAS 51174-13-1)
- 4-(2-(4-Ethylphenyl)quinolin-4-yl)morpholine (CAS 853328-30-0)
- 4'-(Chlorosulfonyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 340759-68-4)
- 4-bromo-1-methyl-pyrrole-2-carbonitrile (CAS 1289207-30-2)
- tert-Butyl N-(2,2-dimethyl-3-oxocyclobutyl)carbamate (CAS 1434141-90-8)
- Tegoprazan Impurity 117 (CAS CATO-C4X-2297117)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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