Dopamine Impurity 48 CAS 500337-08-6
| CAS No. | 500337-08-6 |
| Molecular Formula | C15H15NO3 |
| Molecular Weight | 257.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dopamine Impurity 48 (C15H15NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Dopamine Impurity 48 (CAS 500337-08-6) is a certified pharmaceutical impurity reference standard with the molecular formula C15H15NO3 and a molecular weight of 257.28 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15NO3 |
| Molecular Weight | 257.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 1 |
Related Dopamine Standards
- Dopamine Impurity 73 (CAS CATO-C4X-190873)
- Dopamine Impurity 23 (CAS 1158-27-6)
- Dopamine Impurity 103 (CAS CATO-C4X-1908103)
- Dopamine Impurity 104 (CAS CATO-C4X-1908104)
- Dopamine Impurity 14 (CAS 217657-34-6)
- Dopamine 3-O-Sulfate (CAS 51317-41-0)
- Dopamine 4-O-Sulfate (CAS 38339-02-5)
- Dopamine Impurity (CAS 83442-18-6)
Recommended Standards
- Furosemide Impurity 64 (CAS 116436-17-0)
- Carvedilol impurity 17 (CAS 123119-89-1)
- Avibactam Impurity 15 (CAS 144978-12-1)
- Ketorolac Impurity 23 (CAS 141054-42-4)
- Pemetrexed Impurity 55 (CAS CATO-C4X-172655)
- Empagliflozin Impurity 153 (CAS 219823-47-9)
- Fluvoxamine Impurity 12 (CAS CATO-C4X-195112)
- 2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylpropan-1-amine (CAS 1178088-18-0)
- 2-Chloro-5-(1,3,4-oxadiazol-2-yl)pyridine (CAS 1094240-31-9)
- N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide (CAS 1217846-28-0)
- trans-1,2-Di(2-thienyl)ethylene (CAS 13640-78-3)
- 4-(3-Pyrrolinomethyl)-2-trifluoromethyl-benzophenone (CAS 898764-43-7)
- 2-((4-Ethoxyphenyl)amino)-5,6-dimethylpyrimidin-4-ol (CAS 932279-51-1)
- Calcitonin C-Terminal Flanking Peptide (human) XTFA (CAS 85916-47-8（free base）)
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