1-(2-Chloroethyl)-3-(3-(trifluoromethyl)phenyl)urea CAS 500546-66-7
| CAS No. | 500546-66-7 |
| Molecular Formula | C10H10ClF3N2O |
| Molecular Weight | 266.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 266.65 g/mol gives 1-(2-Chloroethyl)-3-(3-(trifluoromethyl)phenyl)urea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-(2-Chloroethyl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 500546-66-7), a certified reference material (molecular formula C10H10ClF3N2O, MW 266.65 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-Chloroethyl)-3-(3-(trifluoromethyl)phenyl)urea (C10H10ClF3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-Chloroethyl)-3-(3-(trifluoromethyl)phenyl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClF3N2O |
| Molecular Weight | 266.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroethyl Standards
- 1-(2-Chloroethyl)-3-(4-(trifluoromethyl)phenyl)urea (CAS 13908-39-9)
- 1-(2-Chloroethyl)-2-iodobenzene (CAS 1037075-33-4)
- 1-(1-Chloroethyl)-4-iodobenzene (CAS 58114-08-2)
- 1-[3-(2-chloroethyl)phenyl]octan-1-one (CAS 841251-39-6)
- 5-(Bis(2-chloroethyl)amino)-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 62785-09-5)
- 5-(Bis(2-chloroethyl)amino)-6-methylpyrimidine-2,4(1H,3H)-dione (CAS 520-09-2)
- 1-(2-Chloroethyl)-3-(3,4-dichlorophenyl)urea (CAS 15145-37-6)
- N1-(2-chloroethyl)-N2-(2,3-dichlorophenyl)ethane-1,2-diamine (CAS 2514942-62-0)
Recommended Standards
- (E)-N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N,N-dimethylformohydrazonamide (CAS 339029-44-6)
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- 4-Cyano-3-(difluoromethyl)-5-methylpyridine-2-sulfonyl chloride (CAS 1807122-16-2)
- 3-[5-(3-Chloro-4-fluorophenyl)-2-furyl]acrylic acid (CAS 847482-09-1)
- 3-(2-Fluoroethoxy)benzaldehyde (CAS 132838-25-6)
- 1,3-Dimethyl-7-(2-methylallyl)-8-(2-(4-nitrobenzylidene)hydrazinyl)-3,7-dihydro-1H-purine-2,6-dione (CAS 398997-33-6)
- 4-Methylphenyl β-D-galactopyranoside (CAS 3150-22-9)
- Cobalt(II) Sulfamate Hydrate (CAS 14017-41-5)
- 4-(Methylsulfanyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-6-ol (CAS 866131-23-9)
- 2-(2-((Tert-butylamino)methyl)phenoxy)acetic acid (CAS 1279205-26-3)
- 3-(4-Bromophenyl)-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-(1H-imidazol-1-yl)-4,5-dihydro-1H-pyrazole (CAS 496785-20-7)
- Ethyl 2-(6-hydroxy-2-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetate (CAS 1414797-85-5)
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- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
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