8-Methoxy-4-(trifluoromethyl)quinolin-2-ol CAS 503147-99-7
| CAS No. | 503147-99-7 |
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-Methoxy-4-(trifluoromethyl)quinolin-2-ol (CAS 503147-99-7) is a high-purity analytical reference standard with the molecular formula C11H8F3NO2 and a molecular weight of 243.18 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 8-Methoxy-4-(trifluoromethyl)quinolin-2-ol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 8-Methoxy-4-(trifluoromethyl)quinolin-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 6-METHOXY-3-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE (CAS 1371589-18-2)
- 6-Methoxy-2-(trifluoromethyl)quinolin-4-ol (CAS 1701-21-9)
- 5-(2-Methoxy-5-(trifluoromethyl)phenyl)oxazole (CAS 2364584-66-5)
- 6-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 500562-78-7)
- 6-Methoxy-4-(trifluoromethyl)quinolin-2(1H)-one (CAS 328956-13-4)
- 7-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 39975-59-2)
- 7-Methoxy-4-(trifluoromethyl)quinolin-2(1H)-one (CAS 73496-31-8)
- ((6-Methoxy-5-nitropyrimidin-4-yl)oxy)methyl acetate (CAS 136718-69-9)
Recommended Standards
- Daunorubicin Impurity 1 (CAS 51996-45-3)
- Methyl 2-(trifluoromethyl)-1H-indole-5-carboxylate (CAS 2111853-72-4)
- 6-Nitroimidazo[1,2-b]isoquinoline-5,10-dione (CAS 62366-59-0)
- Methyl 5-(trifluoromethyl)-1H-indole-3-carboxylate (CAS 415918-11-5)
- 2-(2-Chloro ethoxy) Ethyl acetate (CAS 14258-40-3)
- 1,1,3,3,5,5,7,7,9,9,11,11-Dodecamethylhexasiloxane (CAS 995-82-4)
- 1-[(2-Chloro-4-fluorophenyl)methyl]-1H-pyrazol-4-amine (CAS 1002033-29-5)
- 2-(2,4-Dichlorophenyl)-5-(4-nitrophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000571-77-6)
- N-(3-cyanophenyl)-2-(1,3-dioxoisoindolin-2-yl)acetamide (CAS 709011-36-9)
- (S)-(+)-4-(2,3-Epoxypropoxy)carbazole (CAS 95093-95-1)
- 1-[3-(Difluoromethyl)-2-methylphenyl]ethanone (CAS 2230840-24-9)
- 4-(Aminomethyl)-2,6-difluorophenol hydrochloride (CAS 220353-10-6)
- 2-Amino-N-(4-(dimethylamino)cyclohexyl)-N-ethylacetamide (CAS 1353960-08-3)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com