7-Methoxy-4-(trifluoromethyl)quinolin-2(1H)-one CAS 73496-31-8
| CAS No. | 73496-31-8 |
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-Methoxy-4-(trifluoromethyl)quinolin-2(1H)-one (CAS 73496-31-8), a certified reference material (molecular formula C11H8F3NO2, MW 243.18 g/mol) for analytical method development and quality control.
Based on its molecular formula C11H8F3NO2, 7-Methoxy-4-(trifluoromethyl)quinolin-2(1H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8F3NO2 |
| Molecular Weight | 243.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 6-METHOXY-3-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE (CAS 1371589-18-2)
- 6-Methoxy-2-(trifluoromethyl)quinolin-4-ol (CAS 1701-21-9)
- 5-(2-Methoxy-5-(trifluoromethyl)phenyl)oxazole (CAS 2364584-66-5)
- 6-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 500562-78-7)
- 6-Methoxy-4-(trifluoromethyl)quinolin-2(1H)-one (CAS 328956-13-4)
- 7-Methoxy-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 39975-59-2)
- 8-Methoxy-4-(trifluoromethyl)quinolin-2-ol (CAS 503147-99-7)
- ((6-Methoxy-5-nitropyrimidin-4-yl)oxy)methyl acetate (CAS 136718-69-9)
Recommended Standards
- 6-Nitroimidazo[1,2-b]isoquinoline-5,10-dione (CAS 62366-59-0)
- Daunorubicin Impurity 1 (CAS 51996-45-3)
- Methyl 2-(trifluoromethyl)-1H-indole-5-carboxylate (CAS 2111853-72-4)
- Methyl 5-(trifluoromethyl)-1H-indole-3-carboxylate (CAS 415918-11-5)
- 5-(2-Fluorophenyl)-4-methylpyridin-2-amine (CAS 1214389-09-9)
- (E)-3-(3-((4-Chlorophenoxy)methyl)-4-methoxyphenyl)acrylic acid (CAS 512809-94-8)
- 3-Chloro-4-(3-(3-methoxyphenyl)-5-oxoimidazolidin-1-yl)benzenesulfonamide (CAS 53298-11-6)
- Urapidil Impurity 72 (CAS 5259-97-2)
- 3-(5-Isobutyl-1,3,4-oxadiazol-2-yl)aniline (CAS 1416341-24-6)
- 3-Methoxy-2-nitroaniline (CAS 16554-47-5)
- 1-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-4-(4-methoxyphenyl)-1H-pyrazol-5-amine (CAS 955964-74-6)
- 1,2-4,4-Difluoromyristoyl-Sn-Glycero-3-Phosphorylcholine (CAS 79962-98-4)
- 1-(1,4-Dimethylpiperidin-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1707582-90-8)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com