2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-phenoxyphenyl)acetamide CAS 503425-66-9
| CAS No. | 503425-66-9 |
| Molecular Formula | C24H24ClN3O2 |
| Molecular Weight | 421.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-phenoxyphenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-phenoxyphenyl)acetamide (CAS 503425-66-9), molecular formula C24H24ClN3O2 and molecular weight 421.92 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-phenoxyphenyl)acetamide (C24H24ClN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H24ClN3O2 |
| Molecular Weight | 421.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- (2E)-2-(4-Chlorophenyl)-3-(dimethylamino)-1-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}prop-2-en-1-one (CAS 478032-53-0)
- 2-(2-{[(2-chlorophenyl)sulfanyl]methyl}-1H-1,3-benzimidazol-1-yl)-N-methyl-N-phenylacetamide (CAS 339101-10-9)
- 2-(2-{[(4-chlorophenyl)sulfanyl]methyl}-1H-1,3-benzimidazol-1-yl)-N-methyl-N-phenylacetamide (CAS 339100-22-0)
- (E)-1-((4-chlorophenyl)sulfonyl)-N'-(2-hydroxybenzylidene)piperidine-4-carbohydrazide (CAS 393852-31-8)
- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N,N-diphenylacetamide (CAS 336180-10-0)
- 2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N,N-diphenylacetamide (CAS 332386-58-0)
- 2-(4-Chlorophenyl)-3-[(4-methoxyphenyl)sulfanyl]quinoline-4-carboxylic acid (CAS 477867-89-3)
- N-(3-chlorophenyl)-2-((4-phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332385-34-9)
Recommended Standards
- CCT251545 (CAS 1661839-45-7)
- 2-(4-chloro-2-methylphenoxy)(3-pyridyl) 4-benzylpiperazinyl ketone (CAS 497060-64-7)
- 2-(2-(5-Methylfuran-2-yl)vinyl)-4,6-bis(trichloromethyl)-1,3,5-triazine (CAS 156360-76-8)
- 2-(4-Chlorobenzenesulfonyl)-3-methanesulfonyl-4-methyl-6-phenylpyridine (CAS 339017-10-6)
- N2-(3-methoxypropyl)pyridine-2,5-diamine (CAS 4928-48-7)
- (2R)-2-amino-2-(4-chloro(2-pyridyl))ethan-1-ol (CAS 1213957-32-4)
- 5-Methoxy-2-(piperazin-1-ylmethyl)phenol (CAS 1249373-00-9)
- Dicyclohexyl(2',6'-dimethyl-[1,1'-biphenyl]-2-yl)phosphine (CAS 298205-46-6)
- trans-1,2,6-trimethylpiperazine (CAS 1354393-55-7)
- 1-(3-Chloro-5-fluorophenyl)cyclopropane-1-carbonitrile (CAS 1314759-91-5)
- o-Tolyl(4-(3-(6-(trifluoromethyl)pyridin-3-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone (CAS 909675-91-8)
- 5-chloro-2-fluoropyrazolo[1,5-a]pyrimidine (CAS 2227206-65-5)
- 3U7W4YOY3R 85-56-3 2-(4'-Chlorobenzoyl)benzoic acid Benzoic acid, o-(p-chlorobenzoyl)- (8CI) Benzoic acid, 2-(4-chlorobenzoyl)- 2-(4-Chlorobenzoyl)benzoic acid AI3-15224 o-(p-Chlorobenzoyl)benzoic acid o-(4-Chlorobenzoyl)benzoic acid 2-(p-Chlorobenzoyl)benzoic acid EINECS 201-615-9 NSC 7825 UNII-3U7W4YOY3R (CAS 85-56-3)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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