2-(4-Chlorobenzenesulfonyl)-3-methanesulfonyl-4-methyl-6-phenylpyridine CAS 339017-10-6
| CAS No. | 339017-10-6 |
| Molecular Formula | C19H16ClNO4S2 |
| Molecular Weight | 421.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Chlorobenzenesulfonyl)-3-methanesulfonyl-4-methyl-6-phenylpyridine (CAS 339017-10-6), molecular formula C19H16ClNO4S2 and molecular weight 421.92 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Chlorobenzenesulfonyl)-3-methanesulfonyl-4-methyl-6-phenylpyridine (C19H16ClNO4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chlorobenzenesulfonyl)-3-methanesulfonyl-4-methyl-6-phenylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16ClNO4S2 |
| Molecular Weight | 421.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chlorobenzenesulfonyl Standards
- 3-(4-Chlorobenzenesulfonyl)-2-hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide (CAS 338956-18-6)
- 1-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrobenzoyl}piperidine (CAS 337921-08-1)
- 4-[(4-Chlorobenzenesulfonyl)methyl]-6-[(2-chlorophenyl)methoxy]-2-methylpyrimidine (CAS 338960-44-4)
- 1-(4-Chlorobenzenesulfonyl)-N'-[(1E)-(4-fluorophenyl)methylidene]piperidine-4-carbohydrazide (CAS 478030-77-2)
- 1-(4-Chlorobenzenesulfonyl)-N'-[(1E)-(4-methylphenyl)methylidene]piperidine-4-carbohydrazide (CAS 478030-74-9)
- 3-(4-Chlorobenzenesulfonyl)-N-[(1E)-(dimethylamino)methylidene]-5-(trifluoromethyl)pyridine-2-carboxamide (CAS 338407-02-6)
- 5-[1-(2-Chlorobenzenesulfonyl)pyrrolidin-2-yl]-3-(2-chlorophenyl)-1,2,4-oxadiazole (CAS 551931-01-2)
- 5-[1-(2-Chlorobenzenesulfonyl)pyrrolidin-2-yl]-3-(3-chlorophenyl)-1,2,4-oxadiazole (CAS 551931-00-1)
Recommended Standards
- 2-(4-chloro-2-methylphenoxy)(3-pyridyl) 4-benzylpiperazinyl ketone (CAS 497060-64-7)
- 2-(4-Methoxyphenyl)-4,6-bis(trichloromethyl)-1,3,5-triazine (CAS 3584-23-4)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(4-phenoxyphenyl)acetamide (CAS 503425-66-9)
- (2E)-2-(4-Chlorophenyl)-3-(dimethylamino)-1-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}prop-2-en-1-one (CAS 478032-53-0)
- 7-Hydroxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 63463-27-4)
- Tert-butyl 4-cyano-2-(methoxymethyl)-2-methyl-3-oxopyrrolidine-1-carboxylate (CAS 2306269-67-8)
- N-Nitroso Bupropion 2'-Chloro Analog (CAS CATO-C4X-120360)
- 6-Iodo-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1359701-92-0)
- 1-(4-Fluorophenyl)-1H-pyrrole-3-carbaldehyde (CAS 288251-69-4)
- tert-Butyl 4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxylate (CAS 960221-97-0)
- 3-Bromo-5-(piperidin-1-ylsulfonyl)pyridin-4-amine (CAS 1352498-02-2)
- 4-(1,5-Dimethyl-1h-pyrazol-4-yl)-2-hydrazinylpyrimidine (CAS 1006341-06-5)
- Tofacitinib Impurity 118 (CAS 1615709-89-1)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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