Brimonidine EP Impurity B CAS 50358-63-9
| CAS No. | 50358-63-9 |
| Molecular Formula | C8H6BrN3 |
| Molecular Weight | 224.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Brimonidine EP Impurity B (C8H6BrN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Brimonidine EP Impurity B (CAS 50358-63-9), a pharmacopoeial impurity reference standard (molecular formula C8H6BrN3, MW 224.06 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Brimonidine EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrN3 |
| Molecular Weight | 224.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Brimonidine Standards
- Brimonidine Impurity 21 (CAS 1378255-24-3)
- Brimonidine EP Impurity A (CAS 91147-43-2)
- Brimonidine Impurity 23 (CAS CATO-C4X-156623)
- Brimonidine Impurity 27 (CAS 185312-10-1)
- Brimonidine Impurity 32 (CAS CATO-C4X-156632)
- Brimonidine Impurity 25 (CAS 135306-57-9)
- Brimonidine Impurity 15 (CAS 91147-46-5)
- Brimonidine Impurity 24 (CAS CATO-C4X-156624)
Recommended Standards
- Sitagliptin Impurity 58 (CAS 667-35-6)
- 918811-38-8 6-Bromophthalazin-1-amine DTXSID70733171 (CAS 918811-38-8)
- 2,4-D D3 (CAS 202480-67-9)
- 7-Bromoquinoxalin-2-amine (CAS 212327-11-2)
- Bendamustine Impurity 40 (CAS CATO-C4X-127140)
- Tizanidine Impurity 59 (CAS CATO-C4X-144559)
- Fingolimod EP Impurity D (CAS 780729-32-0)
- 2-(5-Amino-3-methyl-1H-pyrazol-1-yl)-6-phenylpyrimidin-4(3H)-one (CAS 1171738-69-4)
- 4-[4-(Dimethoxymethyl)pyrimidin-2-yl]phenyl 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 477870-40-9)
- 2-Amino-N-cyclopropyl-3-methyl-N-((S)-1-(thiazol-2-yl)ethyl)butanamide (CAS 1354025-18-5)
- 2-Methoxy-7-methylnaphthalene (CAS 1131-53-9)
- Eldecalcitol Impurity 56 (CAS 66774-82-1)
- 2-(Benzo[b]thiophen-2-yl)-4,4-dimethyl-1,3,2-dioxaborolane (CAS 568572-21-4)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com