6-chloro-2-(difluoromethyl)quinazolin-4-ol CAS 50419-38-0

Purity 97%+In StockPharmaceutical Standards
CAS No.50419-38-0
Molecular FormulaC9H5ClF2N2O
Molecular Weight230.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-chloro-2-(difluoromethyl)quinazolin-4-ol CAS 50419-38-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-chloro-2-(difluoromethyl)quinazolin-4-ol.

CATO supplies 6-chloro-2-(difluoromethyl)quinazolin-4-ol (CAS 50419-38-0), a certified reference material (molecular formula C9H5ClF2N2O, MW 230.60 g/mol) for analytical method development and quality control.

The molecular framework of 6-chloro-2-(difluoromethyl)quinazolin-4-ol (C9H5ClF2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-chloro-2-(difluoromethyl)quinazolin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H5ClF2N2O
Molecular Weight230.60 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1971
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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