4-Bromo-2-methylquinoline CAS 50488-44-3
| CAS No. | 50488-44-3 |
| Molecular Formula | C10H8BrN |
| Molecular Weight | 222.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-2-methylquinoline.
CATO supplies 4-Bromo-2-methylquinoline (CAS 50488-44-3), a certified reference material (molecular formula C10H8BrN, MW 222.08 g/mol) for analytical method development and quality control.
The molecular framework of 4-Bromo-2-methylquinoline (C10H8BrN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Bromo-2-methylquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8BrN |
| Molecular Weight | 222.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2,3-dihydro-1H-indene-1-carbonitrile (CAS 1033811-54-9)
- 3-Bromo-1-methylisoquinoline (CAS 1041263-08-4)
- 4-Bromo-1-methylisoquinoline (CAS 104704-40-7)
- 4-Bromo-6-methylquinoline (CAS 1070879-23-0)
- 4-Bromo-7-methyl-quinoline (CAS 1070879-24-1)
- 5-Bromo-3-methoxypicolinaldehyde (CAS 1087659-24-2)
- 5-Bromo-7-methylquinoline (CAS 1126824-42-7)
- 5-Bromo-6-methylisoquinoline (CAS 1146298-61-4)
Recommended Standards
- 4-(Bromomethyl)quinoline (CAS 5632-16-6)
- 4-Bromo-8-methylquinoline (CAS 36075-68-0)
- 3-Bromonaphthalen-2-amine (CAS 54245-33-9)
- 5-(Bromomethyl)-3-(propan-2-yl)-1,3-oxazolidin-2-one (CAS 78723-67-8)
- 5-Bromo-3-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1111637-68-3)
- 8-Bromo-5-hydroxy-6,7-dimethoxy-2-methyl-4H-chromen-4-one (CAS 1295300-15-0)
- N-(1-carbamothioylcyclopentyl)benzamide (CAS 1274493-24-1)
- Vinorelbine EP Impurity I (CAS CATO-C4X-264210)
- 2-[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]acetonitrile (CAS 852933-96-1)
- 3-Bromo-4,5,7-trichloroquinoline (CAS 1204811-37-9)
- 2-(4-(1H-Imidazol-1-yl)butoxy)benzaldehyde hydrochloride (CAS 1609409-37-1)
- 2-Isobutyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 856167-68-5)
- Methyl 1-Cbz-3-pyrrolidinecarboxylate (CAS 188847-00-9)
- Tau Peptide (304-318) trifluoroacetate salt (CAS 330456-49-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com