Vinorelbine EP Impurity I CAS CATO-C4X-264210
| CAS No. | CATO-C4X-264210 |
| Molecular Formula | C45H53BrN4O8 |
| Molecular Weight | 857.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Vinorelbine EP Impurity I.
As a process- or degradation-related impurity, Vinorelbine EP Impurity I (CAS CATO-C4X-264210, C45H53BrN4O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vinorelbine EP Impurity I (C45H53BrN4O8) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vinorelbine EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C45H53BrN4O8 |
| Molecular Weight | 857.83 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Vinorelbine Standards
- Vinorelbine Impurity 23 (CAS CATO-C4X-264223)
- Vinorelbine Impurity 14 (CAS CATO-C4X-264214)
- Vinorelbine EP Impurity D (CAS CATO-C4X-26425)
- Vinorelbine EP Impurity G (CAS 72311-64-9)
- Vinorelbine Impurity 15 (CAS CATO-C4X-264215)
- Vinorelbine EP Impurity J (CAS 38390-45-3)
- Vinorelbine EP Impurity K (CAS CATO-C4X-264211)
- Vinorelbine Impurity 16 (CAS CATO-C4X-264216)
Recommended Standards
- 17-Bromo-3',4'-didehydro-4'-deoxy-C'-norvincaleukoblastineDISCONTINUED (CAS 89384-09-8)
- Tris(6-methylheptyl) 2,2',2''-(((3-Butoxy-3-oxopropyl)stannanetriyl)tris(sulfanediyl))triacetate (CAS 63438-80-2)
- dimethyl-1,2-oxazol-3-ol (CAS 930-83-6)
- Peptide T (CAS 106362-32-7)
- Rosuvastatin Impurity 256 (CAS 1422954-13-9)
- Nefopam impurity 24 (CAS CATO-C4X-283724)
- Metaraminol Impurity 23 (CAS 2151127-61-4)
- 2-(oxan-4-yl)-3,4-dihydropyrimidin-4-one (CAS 1250122-56-5)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(4-chlorobenzyl)propanoic acid (CAS 1260618-72-1)
- 2-((6-((4-(Furan-2-carbonyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide (CAS 898455-75-9)
- 4-(4-(Methylsulfonyl)-1,4-diazepan-1-yl)aniline (CAS 1018592-95-4)
- (2R,3S,4R,5R)-2,3,4,5,6-Pentaacetoxyhexanoic acid (CAS 17430-71-6)
- 2-(Trifluoromethyl)-9H-purin-6-amine (CAS 2993-06-8)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
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