Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(4-fluorobenzamido)-4-methylthiophene-3-carboxylate CAS 505096-33-3
| CAS No. | 505096-33-3 |
| Molecular Formula | C23H21FN2O5S |
| Molecular Weight | 456.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(4-fluorobenzamido)-4-methylthiophene-3-carboxylate (C23H21FN2O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(4-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 505096-33-3) is a high-purity analytical reference standard with the molecular formula C23H21FN2O5S and a molecular weight of 456.49 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H21FN2O5S |
| Molecular Weight | 456.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(2-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 335410-33-8)
- Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(3-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 505095-59-0)
- Methyl 5-((4-ethoxyphenyl)carbamoyl)-2-(4-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 335406-28-5)
- 2-(4-Ethoxyphenyl)-4-oxo-4H-chromen-3-yl 4-chlorobenzenesulfonate (CAS 298215-03-9)
- Methyl 5-((2-ethoxyphenyl)carbamoyl)-4-methyl-2-(2-(thiophen-2-yl)acetamido)thiophene-3-carboxylate (CAS 505096-52-6)
- N-(2-(5-(2-Ethoxyphenyl)-1-(furan-2-carbonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide (CAS 923244-03-5)
- N-(2-(5-(4-Ethoxyphenyl)-1-(furan-2-carbonyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide (CAS 923122-19-4)
- 9,10-Bis(4-ethoxyphenyl)-2-chloroanthracene (CAS 135965-21-8)
Recommended Standards
- Methyl 5-((2-fluorophenyl)carbamoyl)-4-methyl-2-(2-(o-tolyloxy)acetamido)thiophene-3-carboxylate (CAS 335410-72-5)
- LOBARIC ACID (CAS 522-53-2)
- 264273-08-7 [(1S)-4-Amino-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-oxo-1,3,4,5-tetrahydro-2H-2-benzazepin-2-yl]acetic acid DTXSID30725193 (CAS 264273-08-7)
- Ethyl 2-(2-(2-fluorophenoxy)acetamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate (CAS 518350-22-6)
- 1,2,2,3,3,4,4,5,5,6,6-Undecafluorocyclohexane-1-carbonitrile (CAS 51579-56-7)
- 2-(Tetrahydro-2h-pyran-2-yl)ethanethioamide (CAS 1154976-90-5)
- N-(3,4-Dimethylphenyl)-2-(4-methyl-6-oxopyrimidin-1(6H)-yl)acetamide (CAS 1203167-21-8)
- 1-Ethyl-N-((1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl)-3-methyl-1H-pyrazol-5-amine hydrochloride (CAS 1855947-25-9)
- Methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-ethynylphenyl)propanoate (CAS 188640-59-7)
- Methyl 4-(6-methoxynicotinoyl)benzoate (CAS 898786-08-8)
- 1-Bromo-2-fluoro-3-(methylsulfonyl)-5-nitrobenzene (CAS 1445995-73-2)
- 2-(4-Chlorophenyl)-1H-indene-1,3(2H)-dione (CAS 1146-99-2)
- 4-(methylamino)benzamide hydrochloride (CAS 1193389-02-4)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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