2-Chloro-4,5-difluoropyridine CAS 511522-70-6
| CAS No. | 511522-70-6 |
| Molecular Formula | C5H2ClF2N |
| Molecular Weight | 149.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 149.53 g/mol gives 2-Chloro-4,5-difluoropyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-4,5-difluoropyridine (CAS 511522-70-6) is a high-purity analytical reference standard with the molecular formula C5H2ClF2N and a molecular weight of 149.53 g/mol.
The molecular framework of 2-Chloro-4,5-difluoropyridine (C5H2ClF2N) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4,5-difluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2ClF2N |
| Molecular Weight | 149.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2,3-difluoropyridine (CAS 1214327-63-5)
- 2-Chloro-3,4-difluoropyridine (CAS 1227502-41-1)
- 2-Chloro-3,6-difluoropyridine (CAS 1807031-39-5)
- 5-Chloro-2,4-difluoropyridine (CAS 1807257-52-8)
- 2-Chloro-4,6-difluoropyridine (CAS 34941-89-4)
- 3-Chloro-2,4-difluoropyridine (CAS 851179-01-6)
- 3-Chloro-2,5-difluoropyridine (CAS 851179-00-5)
- 3-Chloro-2,6-difluoropyridine (CAS 52208-56-7)
Recommended Standards
- (S)-4-(Chloromethyl)oxazolidine-2,5-dione (CAS 96165-57-0)
- 2-Oxo-3-oxazolidinecarbonyl chloride (CAS 66313-48-2)
- (R)-4-(Chloromethyl)oxazolidine-2,5-dione (CAS 135920-56-8)
- 3-Chloro-4,5-difluoropyridine (CAS 851178-98-8)
- (3,5-Dimethyl-1h-pyrazol-4-yl)methanol (CAS 89600-69-1)
- 6-Bromo-n-cyclopropyl-2-quinazolinamine (CAS 882670-79-3)
- Methyl 4-cyano-2-formylbenzoate (CAS 1701408-08-3)
- 3,3-Diethyl-1-(hydroxymethyl)indolin-2-one (CAS 797051-83-3)
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- 5,6,7,8-Tetrahydronaphthalen-2-yl(thiophen-2-yl)methanamine (CAS 875163-67-0)
- 2,5-Dimethoxybenzenesulfonyl chloride (CAS 1483-28-9)
- Phloroglucinol Impurity 78 (CAS 18612-99-2)
- Pb,Cd,Cr,Ba,Sb,As,Se In Toy Surface Coating (CAS CATO-CCRM102004)
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