2-Methylpyrido[3,4-b]pyrazine CAS 51208-84-5
| CAS No. | 51208-84-5 |
| Molecular Formula | C8H7N3 |
| Molecular Weight | 145.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Methylpyrido[3,4-b]pyrazine (CAS 51208-84-5), molecular formula C8H7N3 and molecular weight 145.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Methylpyrido[3,4-b]pyrazine (C8H7N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7N3 |
| Molecular Weight | 145.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 3 |
Related Methylpyrido Standards
- 8-Methylpyrido[2,3-b]pyrazine (CAS 1023817-02-8)
- 6-Methylpyrido[2,3-b]pyrazine (CAS 155629-96-2)
- 2-Methylpyrido[2,3-b]pyrazine (CAS 155629-97-3)
- 3-Methylpyrido[3,4-b]pyrazine (CAS 700-80-1)
- 4-Methylpyrido[2,3-d]pyrimidine (CAS 28732-71-0)
- 4-Methylpyrido[3,2-d]pyrimidine (CAS 51674-88-5)
- 4-Methylpyrido[3,4-d]pyrimidine (CAS 51752-73-9)
- 7-Methylpyrido[2,3-b]pyrazine (CAS 397325-35-8)
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