Tizanidine Hydrochloride EP Impurity G CAS 51322-80-6
| CAS No. | 51322-80-6 |
| Molecular Formula | C7H3ClN4S |
| Molecular Weight | 210.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tizanidine Hydrochloride EP Impurity G is closely related to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Tizanidine Hydrochloride EP Impurity G (CAS 51322-80-6, C7H3ClN4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tizanidine Hydrochloride EP Impurity G (C7H3ClN4S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tizanidine Hydrochloride EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3ClN4S |
| Molecular Weight | 210.64 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Tizanidine Standards
- Tizanidine impurity 20 (CAS CATO-C4X-144520)
- Tizanidine impurity 26 (CAS CATO-C4X-144526)
- Tizanidine impurity 29 (CAS CATO-C4X-144529)
- Tizanidine EP Impurity A (CAS 51322-69-1)
- Tizanidine Impurity 56 (CAS CATO-C4X-144556)
- Tizanidine Impurity 55 (CAS CATO-C4X-144555)
- Tizanidine impurity 35 (CAS 32863-29-9)
- Tizanidine Impurity 65 (CAS 67357-54-4)
Recommended Standards
- 5-Chloro-1,3-dimethyl-1H-pyrazole-4-sulfonic acid (CAS 499785-48-7)
- 4-chloro-5,8-difluoro-quinazoline (CAS 1210071-65-0)
- 5-Chloro-1-(4-fluorophenyl)-3-methyl-1h-pyrazole (CAS 882144-05-0)
- 8-chloro-3,5-difluoro-1,7-naphthyridine (CAS 2306276-07-1)
- Piperacillin Impurity 56 (CAS CATO-C4X-173256)
- Edaravone impurity 40 (CAS CATO-C4X-106240)
- Capivasertib Impurity 20 (CAS CATO-C4X-331220)
- 5-Chloro-1-Hexene (CAS 927-54-8)
- Tin(II) palmitate (CAS 35104-88-2)
- n-(2-Chlorophenyl)tetrahydro-2h-thiopyran-3-amine (CAS 1342160-29-5)
- 5-Methylpyridine-2-sulfonyl chloride (CAS 179400-16-9)
- 2-Hydroxy-3-methyl-5-nitrobenzoic acid (CAS 54674-88-3)
- 2-(Chloromethyl)-5-(pyrazin-2-yl)-1,3,4-oxadiazole (CAS 937627-62-8)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com