4-Bromo-2-fluorotoluene CAS 51436-99-8
| CAS No. | 51436-99-8 |
| Molecular Formula | C7H6BrF |
| Molecular Weight | 189.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-2-fluorotoluene.
4-Bromo-2-fluorotoluene (CAS 51436-99-8) is a high-purity analytical reference standard with the molecular formula C7H6BrF and a molecular weight of 189.02 g/mol.
Structurally, 4-Bromo-2-fluorotoluene (C7H6BrF) contains fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 189.02 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Bromo-2-fluorotoluene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6BrF |
| Molecular Weight | 189.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-Bromo-4-fluorotoluene (CAS 1422-53-3)
- 2-Bromo-6-fluorotoluene (CAS 1422-54-4)
- 1-Bromo-2-(fluoromethyl)benzene (CAS 446-47-9)
- 1-Bromo-3-(fluoromethyl)benzene (CAS 456-43-9)
- 1-Bromo-4-(fluoromethyl)benzene (CAS 459-49-4)
- 2-Bromo-3-fluorotoluene (CAS 59907-13-0)
- 3-Bromo-4-fluorotoluene (CAS 452-62-0)
- 3-Bromo-5-fluorotoluene (CAS 202865-83-6)
Recommended Standards
- 4,6-dimethoxypyridine-3-boronic acid (CAS 915021-19-1)
- 4-Bromo-3-fluorotoluene (CAS 452-74-4)
- 3-Fluorobenzyl Bromide (CAS 456-41-7)
- 5-Bromo-2-fluorotoluene (CAS 51437-00-4)
- Methyl 3-nitro-2-[(4-phenylpiperazino)methyl]benzenecarboxylate (CAS 860784-17-4)
- 3-Methoxy-4-nitrobenzimidamide (CAS 878156-44-6)
- 8-Bromo-3-fluoroimidazo[1,2-a]pyrazine (CAS 1956339-18-6)
- (R)-5-Methyl-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one (CAS 1001178-87-5)
- Methyl 5-((tert-butoxycarbonyl)amino)-1H-pyrrole-2-carboxylate (CAS 903570-19-4)
- Ethyl 4-amino-2-mercaptobenzoate (CAS 345910-57-8)
- 2-(Ethoxymethyl)-1,3-dihydroxyanthracene-9,10-dione (CAS 17526-17-9)
- 4-Amino-1-methyl-1H-benzo[f]indole-9-carbonitrile (CAS 251096-50-1)
- [4-(Benzyloxy)-3,5-dibromophenyl]methanol (CAS 249515-07-9)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com