2-(Hydroxymethyl)isonicotinonitrile CAS 51454-63-8

Purity 97%+In StockPharmaceutical Standards
CAS No.51454-63-8
Molecular FormulaC7H6N2O
Molecular Weight134.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Hydroxymethyl)isonicotinonitrile CAS 51454-63-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 134.14 g/mol gives 2-(Hydroxymethyl)isonicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-(Hydroxymethyl)isonicotinonitrile (CAS 51454-63-8), a certified reference material (molecular formula C7H6N2O, MW 134.14 g/mol) for analytical method development and quality control.

The molecular framework of 2-(Hydroxymethyl)isonicotinonitrile (C7H6N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Hydroxymethyl)isonicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H6N2O
Molecular Weight134.14 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1971
Nitrogen Atoms2

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