5-(Hydroxymethyl)picolinonitrile CAS 58553-48-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Hydroxymethyl)picolinonitrile.

5-(Hydroxymethyl)picolinonitrile (CAS 58553-48-3), molecular formula C7H6N2O and molecular weight 134.14 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a hydroxyl group, an ether linkage, an aromatic ring system, 5-(Hydroxymethyl)picolinonitrile is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 134.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(Hydroxymethyl)picolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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