1-(4-Chloro-2-fluorophenyl)piperazine CAS 515160-75-5
| CAS No. | 515160-75-5 |
| Molecular Formula | C10H12ClFN2 |
| Molecular Weight | 214.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-Chloro-2-fluorophenyl)piperazine (CAS 515160-75-5) is a high-purity analytical reference standard with the molecular formula C10H12ClFN2 and a molecular weight of 214.67 g/mol.
Structurally, 1-(4-Chloro-2-fluorophenyl)piperazine (C10H12ClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 214.67 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4-Chloro-2-fluorophenyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClFN2 |
| Molecular Weight | 214.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-(2-Chloro-6-fluorophenyl)piperazine (CAS 1121610-03-4)
- 1-(3-Chloro-4-fluorophenyl)pyrrolidin-3-amine (CAS 1181309-35-2)
- 2-Chloro-6-methoxybenzo[d]thiazol-4-amine (CAS 1190321-02-8)
- (S)-3-chloro-2-fluoro-4-(pyrrolidin-2-yl)aniline (CAS 1213194-41-2)
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- 2-chloro-6-ethyl-1H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 1215221-49-0)
- 1-(4-chloro-2-fluorophenyl)pyrrolidin-3-amine (CAS 1248961-67-2)
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Recommended Standards
- 1-(3-Chloro-5-fluorophenyl)piperazine (CAS 210992-23-7)
- 1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carbonyl chloride (CAS 388088-75-3)
- 1-(3-Chloro-2-fluorophenyl)piperazine (CAS 846031-34-3)
- 2-(1,4-Dioxan-2-yl)ethane-1-sulfonyl chloride (CAS 2091573-19-0)
- 2-(2-Methoxyethoxy)ethanethiol (CAS 88778-21-6)
- N-[(1S,2S)-2-(Dimethylamino)cyclohexyl]-N'-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]thiourea (CAS 1173373-69-7)
- Methyl 2-amino-2-(4-fluoro-3-methylphenyl)acetate (CAS 1249980-37-7)
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- 2-(Naphthalen-1-yl)benzoic acid (CAS 108981-92-6)
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