2-{[4-(difluoromethoxy)phenyl]amino}benzoic acid CAS 51679-46-0
| CAS No. | 51679-46-0 |
| Molecular Formula | C14H11F2NO3 |
| Molecular Weight | 279.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-{[4-(difluoromethoxy)phenyl]amino}benzoic acid (CAS 51679-46-0), a certified reference material (molecular formula C14H11F2NO3, MW 279.24 g/mol) for analytical method development and quality control.
Based on its molecular formula C14H11F2NO3, 2-{[4-(difluoromethoxy)phenyl]amino}benzoic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 279.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11F2NO3 |
| Molecular Weight | 279.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluoromethoxy Standards
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Recommended Standards
- 5-(3,4-Difluorobenzyl)-1-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 1956328-38-3)
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- (1s,4s,6r)-5-(Tert-butoxycarbonyl)-7,7-difluoro-2-oxa-5-azabicyclo[4.1.0]heptane-4-carboxylic acid (CAS 1955473-86-5)
- Methyl (E)-3-((4,4,4-trifluoro-3-oxobut-1-en-1-yl)amino)thiophene-2-carboxylate (CAS 672949-73-4)
- Xanthoxylin (CAS 90-24-4)
- 2-Fluoro-4,5-dimethylphenylboronic acid (CAS 1125394-25-3)
- Tert-butyl 4-(aminomethyl)-4-(4-methoxybenzyl)piperidine-1-carboxylate (CAS 1774896-85-3)
- 3-Amino-2-[4-butoxycarbonyl(piperazino)]pyridine (CAS 1351479-30-5)
- 1-Phenethyl-1H-pyrazol-4-ol (CAS 1595743-71-7)
- N-(5-(4-Aminophenoxy)pentyl)-2-phenoxyacetamide (CAS 102008-71-9)
- 4-Bromo-2-cyano-5-nitrobenzenesulfonyl chloride (CAS 1807170-77-9)
- tert-Butyl 3-[(methylsulfonyl)oxy]-1-azetanecarboxylate (CAS 141699-58-3)
- (2S,3S)-2-(Benzyloxy)pentan-3-amine hydrochloride (CAS 1263094-14-9)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
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