1,8-Naphthyridine-3-carboxylicacid, 1,2-dihydro-2-oxo-7-phenyl- CAS 5175-15-5
| CAS No. | 5175-15-5 |
| Molecular Formula | C15H10N2O3 |
| Molecular Weight | 266.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,8-Naphthyridine-3-carboxylicacid, 1,2-dihydro-2-oxo-7-phenyl- (CAS 5175-15-5) is a high-purity analytical reference standard with the molecular formula C15H10N2O3 and a molecular weight of 266.25 g/mol.
The molecular framework of 1,8-Naphthyridine-3-carboxylicacid, 1,2-dihydro-2-oxo-7-phenyl- (C15H10N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10N2O3 |
| Molecular Weight | 266.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Naphthyridine Standards
- 1,6-Naphthyridine-6(5H)-carboxylic acid, 7,8-dihydro-2-(hydroxymethyl)-, 1,1-dimethylethyl ester (CAS 1868106-31-3)
- 2,2'-bi(1,8-naphthyridine) (CAS 69110-33-4)
- 1,5-Naphthyridine-3-boronic Acid Pinacol Ester (CAS 1356165-79-1)
- 2-Phenyl-1,6-naphthyridine-3-carboxylic acid (CAS 849020-81-1)
- 2-Phenyl-1,7-naphthyridine-4-carboxylic acid (CAS 855521-66-3)
- 1,8-Naphthyridine, 5-chloro-2-(2-methylpropyl)- (CAS 943614-97-9)
- 1,8-Naphthyridine-2,7-dicarboxylic Acid (CAS 84670-42-8)
- 1,8-Naphthyridine-2-butanoic acid (CAS 886362-95-4)
Recommended Standards
- 1,3-Diphenylimidazolidine-2,4,5-trione (CAS 6488-59-1)
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- 1-(4-Nitrophenyl)-4-phenyl-1H-1,2,3-triazole (CAS 2101-57-7)
- 1-Oxo-4-phenyl-1H-isochromene-3-carboxylic acid (CAS 37617-98-4)
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- methyl 4-isocyanatocyclohexane-1-carboxylate (CAS 1486470-18-1)
- 2-((7-Fluoro-1-methyl-4-oxo-1,4-dihydroquinolin-3-yl)sulfinyl)acetic acid (CAS 591781-23-6)
- 1-(2-methoxyethyl)-3,5-dimethyl-1H-pyrazole-4-sulfonyl chloride (CAS 1183972-27-1)
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- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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