2-Phenyl-1,6-naphthyridine-3-carboxylic acid CAS 849020-81-1
| CAS No. | 849020-81-1 |
| Molecular Formula | C15H10N2O2 |
| Molecular Weight | 250.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Phenyl-1,6-naphthyridine-3-carboxylic acid (CAS 849020-81-1), a certified reference material (molecular formula C15H10N2O2, MW 250.25 g/mol) for analytical method development and quality control.
The molecular framework of 2-Phenyl-1,6-naphthyridine-3-carboxylic acid (C15H10N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Phenyl-1,6-naphthyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10N2O2 |
| Molecular Weight | 250.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Phenyl Standards
- 2-Phenyl-1,7-naphthyridine-4-carboxylic acid (CAS 855521-66-3)
- 1,5-Naphthyridine-3-boronic Acid Pinacol Ester (CAS 1356165-79-1)
- 2,2'-bi(1,8-naphthyridine) (CAS 69110-33-4)
- 1,6-Naphthyridine-6(5H)-carboxylic acid, 7,8-dihydro-2-(hydroxymethyl)-, 1,1-dimethylethyl ester (CAS 1868106-31-3)
- 1,8-Naphthyridine-3-carboxylicacid, 1,2-dihydro-2-oxo-7-phenyl- (CAS 5175-15-5)
- 1,8-Naphthyridine, 5-chloro-2-(2-methylpropyl)- (CAS 943614-97-9)
- 1,8-Naphthyridine-2,7-dicarboxylic Acid (CAS 84670-42-8)
- 1,8-Naphthyridine-2-butanoic acid (CAS 886362-95-4)
Recommended Standards
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- 2-Phenylquinazoline-4-carboxylic acid (CAS 7672-01-7)
- 2-Hydrazinyl-6,7-dimethoxy-3-methylquinazolin-4(3H)-one (CAS 945367-99-7)
- tert-Butyl 7-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 188576-49-0)
- 2-(2-Chlorophenyl)-2-piperidin-1-ylacetic acid;hydrochloride (CAS 1779462-24-6)
- 1-Cyclopentyl-5-cyclopropyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1249770-11-3)
- 4-Bromo-3-(bromomethyl)benzonitrile (CAS 190197-86-5)
- Vonoprazan Fumarate Impurity 77 (CAS CATO-C4X-102077)
- 6-Acetyl-2,2-dimethylchroman-4-one (CAS 68799-41-7)
- Triethyl germanium hydride (CAS 1188-14-3)
- 4-benZyl-1-oxa-4,8-diazaspiro[5.5]undecane (CAS 1367727-20-5)
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