Rifaximin-N-Oxide CAS 51963-55-4

Description

The occurrence of Rifaximin-N-Oxide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Rifaximin-N-Oxide (CAS 51963-55-4) is a high-purity analytical reference standard with the molecular formula C43H58N4O13 and a molecular weight of 838.94 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Rifaximin-N-Oxide is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 838.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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