3-(4-Nitrophenyl)-1,3-oxazolidin-2-one CAS 5198-52-7
| CAS No. | 5198-52-7 |
| Molecular Formula | C9H8N2O4 |
| Molecular Weight | 208.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Nitrophenyl)-1,3-oxazolidin-2-one (CAS 5198-52-7), molecular formula C9H8N2O4 and molecular weight 208.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(4-Nitrophenyl)-1,3-oxazolidin-2-one (C9H8N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Nitrophenyl)-1,3-oxazolidin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O4 |
| Molecular Weight | 208.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Nitrophenyl Standards
- 5-(2-Nitrophenyl)-4,5-dihydroisoxazol-5-ol (CAS 153813-83-3)
- 3-(2-Nitrophenyl)oxazolidin-2-one (CAS 90417-72-4)
- 3-(3-nitrophenyl)-1,3-oxazolidin-2-one (CAS 5198-51-6)
- 5-(4-Nitrophenyl)-4,5-dihydroisoxazol-5-ol (CAS 53009-38-4)
- 2-Methyl-2-(3-nitrophenyl)propanamide (CAS 103151-23-1)
- 4-(3-Nitrophenyl)morpholine (CAS 116922-22-6)
- 1-(3-Nitrophenyl)azetidin-3-ol (CAS 1301138-57-7)
- N-[(4-Nitrophenyl)methyl]oxetan-3-amine (CAS 1343399-93-8)
Recommended Standards
- 3-(4-Hydroxy-1H-pyrazolo[3,4-d]pyrimidin-1-yl)propanoic acid (CAS 96096-10-5)
- 3-(Benzo[d][1,3]dioxol-5-yl)-2-oxopropanoic acid (CAS 884-18-4)
- 3,6-Dimethyl-4-oxo-3H,4H-furo[2,3-d]pyrimidine-5-carboxylic acid (CAS 872319-72-7)
- 3-(3-Furan-2-yl-[1,2,4]oxadiazol-5-yl)-propionic acid (CAS 878437-14-0)
- (3-Methoxyphenyl)(oxazol-2-yl)methanone (CAS 898759-47-2)
- n-(2,4,6-Trimethylbenzyl)cyclopropanamine (CAS 926252-55-3)
- 2-Bromo-3-(difluoromethyl)-5-iodo-4-methylpyridine (CAS 1805407-77-5)
- DL-1,4-Bis-o-(Phenylmethyl)-myo inositol (CAS 99782-78-2)
- 5-Chloro-N-(6-chlorobenzo[d]thiazol-2-yl)-2-(methylthio)pyrimidine-4-carboxamide (CAS 879928-23-1)
- (3-Aminopiperidin-1-yl)(2-methoxypyridin-3-yl)methanone (CAS 1409396-83-3)
- 2-(5-(((4-Methoxyphenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)acetic acid (CAS 1092305-54-8)
- eseridine (CAS 25573-43-7)
- Diquafosol Impurity 30 (CAS 221169-12-6；26184-65-6（free base）)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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