5-(4-Nitrophenyl)-4,5-dihydroisoxazol-5-ol CAS 53009-38-4

Purity 97%+In StockPharmaceutical Standards
CAS No.53009-38-4
Molecular FormulaC9H8N2O4
Molecular Weight208.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(4-Nitrophenyl)-4,5-dihydroisoxazol-5-ol CAS 53009-38-4 chemical structure

Description

5-(4-Nitrophenyl)-4,5-dihydroisoxazol-5-ol (CAS 53009-38-4), molecular formula C9H8N2O4 and molecular weight 208.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(4-Nitrophenyl)-4,5-dihydroisoxazol-5-ol (C9H8N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(4-Nitrophenyl)-4,5-dihydroisoxazol-5-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H8N2O4
Molecular Weight208.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Nitrogen Atoms2

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Why CATO?