N-(1,3,4-Thiadiazol-2-yl)isonicotinamide CAS 51988-00-2
| CAS No. | 51988-00-2 |
| Molecular Formula | C8H6N4OS |
| Molecular Weight | 206.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(1,3,4-Thiadiazol-2-yl)isonicotinamide (C8H6N4OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
N-(1,3,4-Thiadiazol-2-yl)isonicotinamide (CAS 51988-00-2), molecular formula C8H6N4OS and molecular weight 206.22 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(1,3,4-Thiadiazol-2-yl)isonicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6N4OS |
| Molecular Weight | 206.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
- 5-(1,3,4-Thiadiazol-2-yl)nicotinamide (CAS 1346687-61-3)
- 4-(1,2,3-Thiadiazol-4-yl)benzoic acid (CAS 187999-31-1)
- N-((1,2,3-thiadiazol-4-yl)methyl)-4-methylpyridin-3-amine (CAS 1343084-38-7)
- n-((1,2,3-Thiadiazol-4-yl)methyl)-2-methylpyridin-3-amine (CAS 1528845-73-9)
- n-((1,2,3-Thiadiazol-4-yl)methyl)-3-methylaniline (CAS 1156893-27-4)
- n-((1,2,3-Thiadiazol-4-yl)methyl)-1-phenylmethanamine (CAS 1156894-76-6)
- 1-(5-Phenyl-1,3,4-thiadiazol-2-yl)ethan-1-amine (CAS 1368961-36-7)
- 4-(1,2,3-Thiadiazol-4-yl)benzamide (CAS 175205-53-5)
Recommended Standards
- Benzyl N-(carbamimidoylmethyl)carbamate (CAS 77390-81-9)
- N-(pyridin-3-yl)-1,2,3-thiadiazole-4-carboxamide (CAS 478261-77-7)
- 8-Methylene-7,8-dihydropyrazolo[4,3-e]thiazolo[3,2-a]pyrimidin-4(1H)-one (CAS 955296-48-7)
- Naphtho[1,8-cd][1,2]oxathiole 2,2-dioxide (CAS 83-31-8)
- 1,4,5,8-Tetraamino-2,7-bis(o-tolyloxy)anthracene-9,10-dione (CAS 88600-63-9)
- Pumosetrag (CAS 153062-94-3)
- ((3AR,4R,6R,6aR)-6-(2-amino-6-oxo-1H-purin-9(6H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl phenyl carbonate (CAS 42139-72-0)
- (5-Fluoro-2-isobutoxyphenyl)(methyl)sulfane (CAS 1379316-21-8)
- 4-Chloro-1H-benzo[d]imidazol-2-amine hydrochloride (CAS 1803612-12-5)
- Octahydro-2H-chromen-2-one (CAS 4430-31-3)
- 3-Fluoro-4'-(methylsulfonyl)-[1,1'-biphenyl]-4-ol (CAS 1032825-01-6)
- 2-Phenylcyclopentanamine (CAS 6604-06-4)
- Rebamipide Impurity 11 (CAS 4876-10-2)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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