5-(1,3,4-Thiadiazol-2-yl)nicotinamide CAS 1346687-61-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1346687-61-3
Molecular FormulaC8H6N4OS
Molecular Weight206.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(1,3,4-Thiadiazol-2-yl)nicotinamide CAS 1346687-61-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(1,3,4-Thiadiazol-2-yl)nicotinamide.

5-(1,3,4-Thiadiazol-2-yl)nicotinamide (CAS 1346687-61-3) is a high-purity analytical reference standard with the molecular formula C8H6N4OS and a molecular weight of 206.22 g/mol.

5-(1,3,4-Thiadiazol-2-yl)nicotinamide (C8H6N4OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(1,3,4-Thiadiazol-2-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H6N4OS
Molecular Weight206.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Nitrogen Atoms4
Sulfur Atoms1

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