4-Amino-2-phenylpyrimidine-5-carbonitrile CAS 52126-76-8
| CAS No. | 52126-76-8 |
| Molecular Formula | C11H8N4 |
| Molecular Weight | 196.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-2-phenylpyrimidine-5-carbonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Amino-2-phenylpyrimidine-5-carbonitrile (CAS 52126-76-8), a certified reference material (molecular formula C11H8N4, MW 196.21 g/mol) for analytical method development and quality control.
The molecular framework of 4-Amino-2-phenylpyrimidine-5-carbonitrile (C11H8N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-2-phenylpyrimidine-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8N4 |
| Molecular Weight | 196.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 6-Amino-2-morpholinopyrimidin-4-ol (CAS 104637-63-0)
- Ethyl 5-amino-6-(methylamino)pyrimidine-4-carboxylate (CAS 1095823-03-2)
- 1-(2-(3-Amino-1h-1,2,4-triazol-1-yl)ethyl)imidazolidin-2-one (CAS 1183476-46-1)
- 5-Amino-1-(tetrahydrofuran-3-yl)-1H-pyrazole-4-carboxamide (CAS 1184913-95-8)
- 3-[2-(4-amino-1h-pyrazol-1-yl)ethyl]-1,3-oxazolidin-2-one (CAS 1250231-63-0)
- 3-(2-(3-Amino-1h-pyrazol-1-yl)ethyl)oxazolidin-2-one (CAS 1341373-68-9)
- 2-Amino-N-((3-methoxypyrazin-2-yl)methyl)acetamide (CAS 1353964-80-3)
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Recommended Standards
- 4-Amino-2-(propylamino)pyrimidine-5-carboxylic acid (CAS 876516-52-8)
- 4-Amino-N-cyclopentyl-1,2,5-oxadiazole-3-carboxamide (CAS 924844-44-0)
- 4-Acetamido-1,3-dimethyl-1H-pyrazole-5-carboxamide (CAS 89239-25-8)
- 4-Pivaloyl-4H-1,2,4-triazole-3-carboxamide (CAS 62735-37-9)
- 1-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(methylamino)ethan-1-one hydrochloride (CAS 1282131-74-1)
- Tert-butyl (3-(fluoromethyl)piperidin-3-yl)carbamate (CAS 1783937-39-2)
- 2-(Hept-1-en-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1014704-08-5)
- 6-Chloro-2-methylpyrimidin-4-ol (CAS 17551-52-9)
- Fasudil Impurity 13 (CAS 56344-32-2)
- 2-Amino-6-methoxybenzoic acid hydrochloride (CAS 108937-85-5)
- 5-phenyl-1$l^{6},2-thiazolidine-1,1,3-trione (CAS 869467-25-4)
- 2-(2-Aminonaphthalen-1-yl)acetic acid (CAS 544444-21-5)
- 5-Bromo-4-chlorothiophene-2-carbonitrile (CAS 1702153-53-4)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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