Mirabegron EP Impurity B HCl CAS 521284-22-0
| CAS No. | 521284-22-0 |
| Molecular Formula | C16H20N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Mirabegron EP Impurity B HCl (CAS 521284-22-0), a pharmacopoeial impurity reference standard (molecular formula C16H20N2OHCl, MW 292.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Mirabegron EP Impurity B HCl (C16H20N2OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 292.81 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Mirabegron EP Impurity B HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20N2O HCl |
| Molecular Weight | 292.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Mirabegron Standards
- Mirabegron Impurity 73 (CAS 100-12-9)
- Mirabegron Impurity 40 (CAS 1154949-80-0)
- rac-Mirabegron-d5 (CAS 1215807-38-7)
- Mirabegron Impurity 147 (CAS 1310279-36-7)
- Mirabegron Impurity 32 (CAS 1310279-36-7 (free base))
- Mirabegron N-t-BOC Impurity (CAS 1329485-55-3)
- Mirabegron Impurity 139 (CAS 1330277-46-7)
- Mirabegron Impurity 62 (CAS 135365-07-0)
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- (4-Bromo-2,6-dimethylphenyl)methanamine (CAS 1114822-90-0)
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- 3-Amino-3-(3-chloro-4-fluorophenyl)propan-1-ol (CAS 787615-36-5)
- 5-Bromo-4-mercaptonicotinonitrile (CAS 1706465-17-9)
- 1-(2,4,6-Trimethylbenzyl)-1,4-diazepane (CAS 690632-22-5)
- 2-Phenyl-2H-benzo[d][1,2,3]triazole 1-oxide (CAS 51750-18-6)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com