2,3-Dihydro-1H-indene-4-sulfonyl chloride CAS 52205-81-9

Purity 97%+In StockPharmaceutical Standards
CAS No.52205-81-9
Molecular FormulaC9H9ClO2S
Molecular Weight216.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,3-Dihydro-1H-indene-4-sulfonyl chloride CAS 52205-81-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,3-Dihydro-1H-indene-4-sulfonyl chloride.

2,3-Dihydro-1H-indene-4-sulfonyl chloride (CAS 52205-81-9), molecular formula C9H9ClO2S and molecular weight 216.68 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2,3-Dihydro-1H-indene-4-sulfonyl chloride (C9H9ClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2,3-Dihydro-1H-indene-4-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H9ClO2S
Molecular Weight216.68 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1971
Halogen ContentCl-containing
Sulfur Atoms1

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