2-{[(2-chlorophenyl)methyl]sulfanyl}acetic acid CAS 66516-65-2
| CAS No. | 66516-65-2 |
| Molecular Formula | C9H9ClO2S |
| Molecular Weight | 216.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-{[(2-chlorophenyl)methyl]sulfanyl}acetic acid (CAS 66516-65-2), a certified reference material (molecular formula C9H9ClO2S, MW 216.68 g/mol) for analytical method development and quality control.
The molecular framework of 2-{[(2-chlorophenyl)methyl]sulfanyl}acetic acid (C9H9ClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H9ClO2S |
| Molecular Weight | 216.68 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related chlorophenyl Standards
- 3-[(3-chlorophenyl)sulfanyl]propanoic acid (CAS 1132-52-1)
- Methyl 2-((4-chlorophenyl)thio)acetate (CAS 15446-15-8)
- 2-((4-Chlorophenyl)thio)propanoic acid (CAS 18527-12-3)
- 2-(3-Chlorophenyl)-2-(methylthio)acetic acid (CAS 29270-27-7)
- 2-[(2-chlorophenyl)sulfanyl]propanoic acid (CAS 99585-15-6)
- 2-{[(3-chlorophenyl)methyl]sulfanyl}acetic acid (CAS 34722-33-3)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}acetic acid (CAS 90649-82-4)
- 3-[(2-chlorophenyl)sulfanyl]propanoic acid (CAS 99585-16-7)
Recommended Standards
- 2,3-Dihydro-1H-indene-4-sulfonyl chloride (CAS 52205-81-9)
- 2,3-Dihydro-1H-indene-2-sulfonyl chloride (CAS 496946-74-8)
- 2-Methoxy-4-(methylthio)benzoyl chloride (CAS 69883-78-9)
- 2-(5-Chloro-2-(methylthio)phenyl)acetic acid (CAS 383135-57-7)
- Benzoic acid potassium (CAS 582-25-2)
- 2,4-Dimethyl-5-(pyridin-4-yl)-1H-pyrazol-3(2H)-one (CAS 90280-22-1)
- 3,4-Dihydro-2H-benzo[b][1,4]oxazine-2-carbothioamide (CAS 92659-38-6)
- N-(2-(5-Acetylthiophen-2-yl)ethyl)-3-(thiophen-3-yl)acrylamide (CAS 2035008-06-9)
- 2-(2-Oxo-2H-chromen-4-yl)acetic acid (CAS 24526-73-6)
- Phenylephrine Impurity 92 (CAS CATO-C4X-146792)
- Oseltamivir EP Impurity E (CAS 208720-71-2)
- tert-Butyl 2-(1-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzoyl)-3-hydroxyazetidin-3-yl)piperidine-1-carboxylate (CAS 1415559-49-7)
- Calcium Dobesilate Impurity 2 (CAS CATO-C4X-20512)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com