4-(4-Chlorophenyl)-3-methyl-4-oxobutanoic acid CAS 52240-25-2
| CAS No. | 52240-25-2 |
| Molecular Formula | C11H11ClO3 |
| Molecular Weight | 226.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-(4-Chlorophenyl)-3-methyl-4-oxobutanoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-(4-Chlorophenyl)-3-methyl-4-oxobutanoic acid (CAS 52240-25-2), a certified reference material (molecular formula C11H11ClO3, MW 226.66 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(4-Chlorophenyl)-3-methyl-4-oxobutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClO3 |
| Molecular Weight | 226.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)tetrahydrofuran-3-carboxylic acid (CAS 1035261-04-1)
- trans-1-(4-Chlorophenyl)-3-hydroxycyclobutanecarboxylic acid (CAS 1145681-01-1)
- N'-(1-(2-Chlorophenyl)ethylidene)-2-hydroxyacetohydrazide (CAS 122432-93-3)
- Methyl 4-(3-chlorophenyl)-4-oxobutanoate (CAS 1249761-08-7)
- Methyl 2-((4-chlorophenyl)(hydroxy)methyl)acrylate (CAS 131469-67-5)
- 2-(4-Chlorophenyl)tetrahydrofuran-3-carboxylic acid (CAS 1341445-99-5)
- 1-(4-Chlorophenyl)-3-hydroxycyclobutanecarboxylic acid (CAS 1353636-65-3)
- 3-(4-Chlorophenyl)-3-hydroxycyclobutane-1-carboxylic acid (CAS 1431568-54-5)
Recommended Standards
- 4-(4-Chlorophenyl)-2-methyl-4-oxobutanoic acid (CAS 52240-20-7)
- 4-(6-Chloropyrimidin-4-yl)-1-methylpiperazin-2-one (CAS 945896-90-2)
- 4-(4-Chloro-3-methylphenyl)-4-oxobutanoic acid (CAS 54557-91-4)
- 4-(allyloxy)-2-chloro-5-methoxybenZaldehyde (CAS 692279-00-8)
- Diethyl (1,1-difluoro-2-hydroxy-4-phenylbutyl)phosphonate (CAS 481053-33-2)
- 4-Amino-5-chloro-6'-methoxy-[2,3'-bipyridine]-6-carboxylic acid (CAS 496852-31-4)
- 1-(2-Chloro-6-fluorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1249544-27-1)
- 1-(2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl)piperidine-3-carboxylic acid (CAS 1708268-55-6)
- 7-Hydroxy-1,4-dimethylquinolin-2(1H)-one (CAS 73290-60-5)
- 4-(4-(Benzyloxy)-2-methylbenzoyl)-3-hydroxy-5-(4-hydroxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 488840-67-1)
- 6-Chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1190322-06-5)
- Benzyl 3-(bromomethyl)pyrrolidine-1-carboxylate (CAS 1353952-24-5)
- 7-Chloro-2-(pyridin-3-yl)-4H-chromen-4-one (CAS 1920-53-2)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
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