N,N'-(1,4-Phenylene)bis(4-aminobenzenesulfonamide) CAS 52257-15-5

Purity 97%+In StockPharmaceutical Standards
CAS No.52257-15-5
Molecular FormulaC18H18N4O4S2
Molecular Weight418.49 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N,N'-(1,4-Phenylene)bis(4-aminobenzenesulfonamide) CAS 52257-15-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N,N'-(1,4-Phenylene)bis(4-aminobenzenesulfonamide).

N,N'-(1,4-Phenylene)bis(4-aminobenzenesulfonamide) (CAS 52257-15-5) is a high-purity analytical reference standard with the molecular formula C18H18N4O4S2 and a molecular weight of 418.49 g/mol.

N,N'-(1,4-Phenylene)bis(4-aminobenzenesulfonamide) (C18H18N4O4S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N,N'-(1,4-Phenylene)bis(4-aminobenzenesulfonamide) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H18N4O4S2
Molecular Weight418.49 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1971
Nitrogen Atoms4
Sulfur Atoms2

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