3-(2,5-Dihydroxyphenyl)isobenzofuran-1(3H)-one CAS 52301-63-0

Purity 97%+In StockPharmaceutical Standards
CAS No.52301-63-0
Molecular FormulaC14H10O4
Molecular Weight242.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2,5-Dihydroxyphenyl)isobenzofuran-1(3H)-one CAS 52301-63-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 242.23 g/mol gives 3-(2,5-Dihydroxyphenyl)isobenzofuran-1(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(2,5-Dihydroxyphenyl)isobenzofuran-1(3H)-one (CAS 52301-63-0), molecular formula C14H10O4 and molecular weight 242.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(2,5-Dihydroxyphenyl)isobenzofuran-1(3H)-one (C14H10O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(2,5-Dihydroxyphenyl)isobenzofuran-1(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H10O4
Molecular Weight242.23 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1971

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