N-Cyclohexyl-4-nitrobenzenesulfonamide CAS 52374-26-2
| CAS No. | 52374-26-2 |
| Molecular Formula | C12H16N2O4S |
| Molecular Weight | 284.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies N-Cyclohexyl-4-nitrobenzenesulfonamide (CAS 52374-26-2), a certified reference material (molecular formula C12H16N2O4S, MW 284.33 g/mol) for analytical method development and quality control.
The molecular framework of N-Cyclohexyl-4-nitrobenzenesulfonamide (C12H16N2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O4S |
| Molecular Weight | 284.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- N-Cyclohexyl-2-nitrobenzenesulfonamide (CAS 77516-53-1)
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- 5-Cyclohexyl-2-(4-methoxyphenyl)pyrimidin-4(1H)-one (CAS 61442-44-2)
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- 6-Phenylpyridazin-3(2H)-one (CAS 2166-31-6)
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