(5-Bromo-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetic acid CAS 5238-66-4
| CAS No. | 5238-66-4 |
| Molecular Formula | C10H6BrNO4 |
| Molecular Weight | 284.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (5-Bromo-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetic acid (CAS 5238-66-4), a certified reference material (molecular formula C10H6BrNO4, MW 284.06 g/mol) for analytical method development and quality control.
(5-Bromo-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetic acid (C10H6BrNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (5-Bromo-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6BrNO4 |
| Molecular Weight | 284.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-(5-Bromo-1,3-dioxo-2,3-dihydro-1h-isoindol-2-yl)acetic acid (CAS 19244-37-2)
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