Z-Gly-Gly-His-OH CAS 52396-73-3
| CAS No. | 52396-73-3 |
| Molecular Formula | C18H21N5O6 |
| Molecular Weight | 403.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Z-Gly-Gly-His-OH is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Z-Gly-Gly-His-OH (CAS 52396-73-3), molecular formula C18H21N5O6 and molecular weight 403.39 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H21N5O6, Z-Gly-Gly-His-OH contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 403.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Z-Gly-Gly-His-OH meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H21N5O6 |
| Molecular Weight | 403.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 5 |
Recommended Standards
- 6-Benzylaminopurine 9-(b-D-glucoside) (CAS 4294-17-1)
- Z-Gly-Pro-OSu (C-1885.0005) (CAS 38417-02-6)
- 3-(2,6-Difluorophenyl)-4-((3-(trifluoromethyl)phenoxy)methyl)thiazole-2(3H)-thione (CAS 866153-95-9)
- Tadalafil Impurity 166 (CAS CATO-C4X-1087166)
- 2-[2-methoxy-4-(prop-2-en-1-yl)phenoxymethyl]oxirane (CAS 36014-34-3)
- 2,5-Dimethyl-1-(pyridin-4-yl)-1H-pyrrole-3-carbaldehyde (CAS 431980-51-7)
- 2-Amino-6-heptenoic Acid HCl (CAS 89895-48-7)
- 1,3-Dichlorocyclohexane (CAS 55887-78-0)
- 3-(ethylamino)-N-methylpropanamide hydrochloride (CAS 1803609-52-0)
- 1-hydroxycyclobutane-1-carboxamide (CAS 1247705-07-2)
- 1-chloro-2-(chloromethyl)-3-methoxybenzene (CAS 344294-26-4)
- Vortioxetine Impurity 40 (CAS CATO-C4X-105640)
- Dequalinium impurity 25 (CAS CATO-C4X-193625)
- C-Peptide 1 (rat) (CAS 41475-27-8)
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