4,6-Dichloro-1-indanone CAS 52397-81-6
| CAS No. | 52397-81-6 |
| Molecular Formula | C9H6Cl2O |
| Molecular Weight | 201.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4,6-Dichloro-1-indanone (CAS 52397-81-6) is a high-purity analytical reference standard with the molecular formula C9H6Cl2O and a molecular weight of 201.05 g/mol.
The molecular framework of 4,6-Dichloro-1-indanone (C9H6Cl2O) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 4,6-Dichloro-1-indanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6Cl2O |
| Molecular Weight | 201.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
Related Dichloro Standards
- 3,5-Dichloro-6-methyl-2H-indazole (CAS 1207175-10-7)
- 6,8-Dichloro-2-methylimidazo[1,2-a]pyridine (CAS 121082-25-5)
- 4,6-Dichloro-2-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1352394-46-7)
- 2,5-Dichloro-1-methyl-1H-benzimidazole (CAS 15965-64-7)
- 2,6-Dichloro-1-methyl-1H-benzo[d]imidazole (CAS 15965-65-8)
- 4,6-Dichloro-1-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1638771-16-0)
- 3,4-Dichloro-1H-indol-7-amine (CAS 165669-12-5)
- 2,4-Dichloro-1-(prop-2-yn-1-yloxy)benzene (CAS 17061-90-4)
Recommended Standards
- 4,5-Dichloro-2,3-dihydro-1H-inden-1-one (CAS 69392-64-9)
- 4,6-Dichloro-3-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 39921-23-8)
- 3-Chloro-3-(4-chlorobenzyl)-3H-diazirine (CAS 91309-66-9)
- 4,6-Dichloro-3-methylbenzofuran (CAS 81078-72-0)
- 2-bromo-7-chloro-Quinoxaline (CAS 89891-64-5)
- 2-Amino-4-(4-bromophenyl)pyrimidine (CAS 392326-81-7)
- 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-sulfonyl chloride (CAS 1423032-89-6)
- (4-Bromo-3-fluorophenyl)(3,3-dimethylazetidin-1-yl)methanone (CAS 1810069-98-7)
- (R)-5-Bromospiro[indene-1,5'-oxazolidine]-2',3,4'(2H)-trione (CAS 1889291-53-5)
- Phosphine, 1,2-ethanediylbis[[2-(1-methylethyl)phenyl]phenyl-, (1S,1′S)- (CAS 794526-19-5)
- (1R)-1-(mercaptomethyl)-7,7-dimethylbicyclo[2.2.1]Heptan-2-ol (CAS 71242-59-6)
- Glipizide EP Impurity J (CAS 1076198-09-8)
- NHI 2 (CAS 1269802-97-2)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com