(S)-2-Amino-3-(6-(trifluoromethyl)-1H-indol-3-yl)propanoic acid CAS 52448-18-7
| CAS No. | 52448-18-7 |
| Molecular Formula | C12H11F3N2O2 |
| Molecular Weight | 272.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(S)-2-Amino-3-(6-(trifluoromethyl)-1H-indol-3-yl)propanoic acid (CAS 52448-18-7), molecular formula C12H11F3N2O2 and molecular weight 272.22 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C12H11F3N2O2, (S)-2-Amino-3-(6-(trifluoromethyl)-1H-indol-3-yl)propanoic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 272.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures (S)-2-Amino-3-(6-(trifluoromethyl)-1H-indol-3-yl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11F3N2O2 |
| Molecular Weight | 272.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related S Standards
- (S)-2-Amino-3-(7-(trifluoromethyl)-1H-indol-3-yl)propanoic acid (CAS 143266-28-8)
- 4-(2-{2-[(4-amino-1,2,5-oxadiazol-3-yl)oxy]ethoxy}ethoxy)-1,2,5-oxadiazol-3-amine (CAS 145958-85-6)
- 1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-phenyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 296791-84-9)
- 4-(5-Amino-7-oxo-3,7-dihydro-2H-[1,2,3]triazolo[4,5-d]pyrimidin-2-yl)benzoic acid (CAS 38065-07-5)
- 5-(5-Amino-4-cyano-1H-pyrazol-1-yl)isophthalic acid (CAS 873773-67-2)
- Ethyl 2-amino-5-(trifluoromethyl)-1H-indole-3-carboxylate (CAS 339278-08-9)
- 4-Amino-6-((4-fluoro-1H-indol-5-yl)oxy)pyrimidine-5-carbaldehyde (CAS 919485-93-1)
- 4-Amino-6-((6-fluoro-1H-indol-5-yl)oxy)pyrimidine-5-carbaldehyde (CAS 919485-94-2)
Recommended Standards
- (E)-6,6'-(Diazene-1,2-diyl)dipicolinicacid (CAS 85322-81-2)
- [2-Methyl-5-(4-trifluoromethoxy-phenyl)-furan-3-yl]-methanol (CAS 672930-64-2)
- (1-Methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanol (CAS 318469-22-6)
- (1-(4-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)methanol (CAS 218631-47-1)
- (S)-2-(2-chloro-5-nitrophenyl)pyrrolidine (CAS 1213589-15-1)
- Methyl 6-methoxy-5-methylpyrimidine-4-carboxylate (CAS 1353499-28-1)
- 3-Chloro-4-phenoxyaniline hydrochloride (CAS 35734-64-6)
- 2-Bromo-3-(bromomethyl)-5-(difluoromethyl)-6-methylpyridine (CAS 1806873-54-0)
- Piperaquine Phosphate (CAS 85547-56-4)
- 6-Ethyl-2-(4-methoxyphenyl)quinoline-4-carboxylic acid (CAS 861412-41-1)
- N-phenyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-[1,1'-biphenyl]-4-amine (CAS 1338803-75-0)
- 2,6-Dibromophenol (CAS 608-33-3)
- 1-(4-Amino-2,6-dichlorophenyl)pyrrolidin-2-one (CAS 954269-40-0)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com