4-(Piperazin-1-ylmethyl)quinoline CAS 524673-95-8
| CAS No. | 524673-95-8 |
| Molecular Formula | C14H17N3 |
| Molecular Weight | 227.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Piperazin-1-ylmethyl)quinoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(Piperazin-1-ylmethyl)quinoline (CAS 524673-95-8), molecular formula C14H17N3 and molecular weight 227.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(Piperazin-1-ylmethyl)quinoline (C14H17N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Piperazin-1-ylmethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17N3 |
| Molecular Weight | 227.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 3 |
Related Piperazin Standards
- 2-(Piperazin-1-ylmethyl)quinoline (CAS 118630-28-7)
- (4-Methyl-piperazin-1-yl)-[1,4]oxazepan-6-yl-methanone (CAS 1316227-53-8)
- 1-(Piperazin-1-yl)-2-(piperidin-4-yloxy)ethan-1-one (CAS 902836-10-6)
- 2-Methyl-8-(piperazin-1-yl)quinoline (CAS 282547-42-6)
- 3-Methyl-2-(piperazin-1-yl)quinoline (CAS 348133-74-4)
- 4-Methyl-2-piperazin-1-yl-quinoline (CAS 50693-78-2)
- 6-Methyl-8-(piperazin-1-yl)quinoline (CAS 796851-63-3)
- 8-(piperazin-1-ylmethyl)quinoline (CAS 929974-85-6)
Recommended Standards
- 4-(Naphthalen-2-yl)piperidin-4-ol (CAS 200875-27-0)
- 4-(tert-Butyl)-6-phenylpyrimidin-2-amine (CAS 313505-80-5)
- 4-(Naphthalen-1-ylmethyl)morpholine (CAS 2862-82-0)
- 4-[(2-phenylpropyl)amino]phenol (CAS 940366-56-3)
- 2-methyl-octahydropyrano[4,3-b]morpholine hydrochloride (CAS 1427378-62-8)
- (3R,4S,5S,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one (CAS 82598-84-3)
- 2-Bromo-4-phenylquinazoline (CAS 354574-58-6)
- 2-Chloro-3-(pyridin-4-yl)-5-(trifluoromethyl)pyridine (CAS 1214366-98-9)
- Methyl 2-(5-bromothiophen-2-yl)acetate (CAS 67137-56-8)
- Olaparib Impurity 18 (CAS 2250243-17-3)
- 5-Bromo-2-fluoro-3-methoxybenzaldehyde (CAS 1779832-66-4)
- 1-(4-Methylcyclohexyl)-1H-pyrrole (CAS 745028-41-5)
- 2-Fluoro-N-(6-methylisoxazolo[5,4-b]pyridin-3-yl)benzamide (CAS 1105206-86-7)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
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