Olaparib Impurity 18 CAS 2250243-17-3
| CAS No. | 2250243-17-3 |
| Molecular Formula | C24H25FN4O3 |
| Molecular Weight | 436.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Olaparib Impurity 18 (CAS 2250243-17-3, C24H25FN4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Olaparib Impurity 18 (C24H25FN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Olaparib Impurity 18 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H25FN4O3 |
| Molecular Weight | 436.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib Impurity 116 (CAS CATO-C4X-1135116)
- Olaparib Impurity 70 (CAS CATO-C4X-113570)
- Olaparib Impurity 52 (CAS CATO-C4X-113552)
- Olaparib (CAS 763113-22-0)
- Olaparib Impurity 122 (CAS CATO-C4X-1135122)
- Olaparib Impurity 123 (CAS CATO-C4X-1135123)
- Olaparib Impurity 124 (CAS CATO-C4X-1135124)
- Olaparib Impurity 125 (CAS CATO-C4X-1135125)
Recommended Standards
- Linezolid Impurity 93 (CAS CATO-C4X-107393)
- Oseltamivir Impurity 23 (CAS 1132659-94-9)
- Apremilast impurity 90 (CAS CATO-C4X-100990)
- isopropyl (2-(2-methoxy-4-(methylsulfonamido)-5-phenoxyphenyl)-2-oxoethyl)carbamate (CAS CATO-C4X-1826143)
- Gadobutrol Impurity 181 (CAS CATO-C4X-2120181)
- Cefradine Impurity C17 (CAS 70287-30-8)
- Cefepime Impurity 27 (CAS CATO-C4X-119327)
- N-(4-Fluorophenyl)-2-(3-formyl-1h-indol-1-yl)acetamide (CAS 428487-58-5)
- 4-(Chloromethyl)quinoline (CAS 5632-17-7)
- Ilaprazole Impurity 31 Hydrochloride (CAS CATO-C4X-1130174)
- 2-Oxoadamantane-1-carboxylic acid (CAS 40556-86-3)
- N-Methyl-2-vinylaniline (CAS 5339-28-6)
- 3,7,8-Trichloro-5-methoxy-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1437454-44-8)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com