2-(2-Chloro-4-fluorophenyl)pyrrolidine CAS 524674-22-4
| CAS No. | 524674-22-4 |
| Molecular Formula | C10H11ClFN |
| Molecular Weight | 199.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2-Chloro-4-fluorophenyl)pyrrolidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(2-Chloro-4-fluorophenyl)pyrrolidine (CAS 524674-22-4), a certified reference material (molecular formula C10H11ClFN, MW 199.65 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H11ClFN, 2-(2-Chloro-4-fluorophenyl)pyrrolidine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 199.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2-Chloro-4-fluorophenyl)pyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11ClFN |
| Molecular Weight | 199.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1-(3-Chloro-4-fluorophenyl)pyrrolidine (CAS 1000339-33-2)
- N-[(2-Chloro-4-fluorophenyl)methyl]cyclopropanamine (CAS 1016534-10-3)
- 1-(2-Chloro-6-fluorobenzyl)cyclopropan-1-amine (CAS 1017133-42-4)
- (1-(2-Chloro-6-fluorophenyl)cyclopropyl)methanamine (CAS 1039952-82-3)
- 1-(2-Chloro-6-fluorophenyl)cyclobutanamine (CAS 1094341-12-4)
- 3-Chloro-N-(cyclopropylmethyl)-2-fluoroaniline (CAS 1156168-46-5)
- 5-Chloro-N-(cyclopropylmethyl)-2-fluoroaniline (CAS 1156168-88-5)
- 4-Chloro-N-(cyclopropylmethyl)-2-fluoroaniline (CAS 1157338-17-4)
Recommended Standards
- [(2-Chloro-6-fluorophenyl)methyl](prop-2-en-1-yl)amine (CAS 62924-63-4)
- 2-(3-Chloro-4-fluorophenyl)pyrrolidine (CAS 298690-78-5)
- 8-chloro-6-fluoro-5-methyl-1,2,3,4-tetrahydroquinoline (CAS 1862410-77-2)
- 2-Chloro-3-fluoro-7,7-dimethyl-6,7-dihydro-5H-cyclopenta[b]pyridine (CAS 2812356-20-8)
- 3-(Bromomethyl)-4-fluoropyridine (CAS 1227585-48-9)
- 2-(4-Fluorophenyl)-8-hydroxy-6-methoxyisoquinolin-1(2H)-one (CAS 1956376-58-1)
- 2,4-Dichloro-5-methylbenzoic acid (CAS 6660-59-9)
- (3-(4-Fluorophenyl)-4,5-dihydroisoxazol-5-yl)methanol (CAS 472976-35-5)
- Methyl 6-benzyl-4-hydroxy-5-oxo-5,6-dihydro-2,6-naphthyridine-3-carboxylate (CAS 1392839-33-6)
- 4-Amino-2,5-dibromofuran-3-carboxylic acid (CAS 1427504-40-2)
- 3-(3-(1,3-Dioxolan-2-yl)benzoyl)benzonitrile (CAS 898778-95-5)
- 2,5-Dichloro-m-terphenyl (CAS 215508-04-6)
- Amiloride EP Impurity C (CAS 76599-74-1)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com