2,5-Dichloro-N-(pyridin-3-yl)thiophene-3-carboxamide CAS 524924-26-3
| CAS No. | 524924-26-3 |
| Molecular Formula | C10H6Cl2N2OS |
| Molecular Weight | 273.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,5-Dichloro-N-(pyridin-3-yl)thiophene-3-carboxamide (CAS 524924-26-3), molecular formula C10H6Cl2N2OS and molecular weight 273.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,5-Dichloro-N-(pyridin-3-yl)thiophene-3-carboxamide (C10H6Cl2N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2,5-Dichloro-N-(pyridin-3-yl)thiophene-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6Cl2N2OS |
| Molecular Weight | 273.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetonitrile (CAS 775351-55-8)
- 2-Amino-4,6-bis(trifluoromethyl)pyridine-3-carboxamide (CAS 89990-38-5)
- 1-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one (CAS 2304634-90-8)
- 2-Bromo-4-Fluoro-1-(Piperazinomethyl)Benzene (CAS 460094-97-7)
- 2-(4-(Tert-butoxycarbonyl)piperazine-1-carbonyl)cyclopropane-1-carboxylic acid (CAS 1160474-45-2)
- (5S)-5-cyclopropylmorpholin-3-one (CAS 1357279-38-9)
- 4-Amino-6-(difluoromethyl)-2-methoxypyridine-3-sulfonamide (CAS 1806920-86-4)
- 1-(4,5-Diphenyloxazol-2-yl)-3-ethylurea (CAS 35629-54-0)
- GACYCLIDINE HYDROCHLORIDE (1R, 2S) (CAS 68134-81-6)
- Fluorohydroxyandrostenedione (CAS 357-09-5)
- Ethyl 1-(3-(trifluoromethyl)benzyl)-1H-pyrazole-4-carboxylate (CAS 1035224-53-3)
- 3-Acetamido-4,5-dimethoxybenzoic acid (CAS 871892-91-0)
- ethyl 5-(4-chlorophenyl)-1-methyl-1H-pyrazole-3-carboxylate (CAS 864426-88-0)
- Peptide 431 (CAS CATO-CPTD788431)
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