2,8-Dioxaspiro[4.5]decane-1,3-dione CAS 5270-49-5
| CAS No. | 5270-49-5 |
| Molecular Formula | C8H10O4 |
| Molecular Weight | 170.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,8-Dioxaspiro[4.5]decane-1,3-dione (CAS 5270-49-5), molecular formula C8H10O4 and molecular weight 170.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,8-Dioxaspiro[4.5]decane-1,3-dione (C8H10O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2,8-Dioxaspiro[4.5]decane-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10O4 |
| Molecular Weight | 170.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Dioxaspiro Standards
- 2,8-Dioxaspiro[4.5]decane-1,4-dione (CAS 2092415-35-3)
- 6,10-Dioxaspiro[4.5]decane-7,9-dione (CAS 58093-05-3)
- 1,9-Dioxaspiro[5.5]undecan-4-one (CAS 1330756-23-4)
- 1,5-Dioxaspiro[5.5]undecan-3-one (CAS 158632-48-5)
- (3S)-1,4-dioxaspiro[4.5]decane-3-carbaldehyde (CAS 99744-77-1)
- 1,4-Dioxaspiro[4.5]decane-2-carbaldehyde (CAS 92822-62-3)
- 1,4-Dioxaspiro[4.5]decane-6-carbaldehyde (CAS 57091-28-8)
- 1,4-dioxaspiro[4.5]decane-8-carbaldehyde (CAS 93245-98-8)
Recommended Standards
- 2,5-Dimethylidenehexanedioic acid (CAS 4481-41-8)
- 2,5-Dimethyl-2,4-hexadienedioic acid (CAS 20514-41-4)
- 2-Cyclopropyl-3,6-difluorophenol (CAS 2451902-59-1)
- 2,4-Dioxocyclohexyl acetate (CAS 366024-03-5)
- (4Z)-4-{[(5-chloro-2-hydroxyphenyl)amino]methylidene}-3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 320425-01-2)
- 4-(3,4-Difluorophenyl)oxazolidin-2-one (CAS 225641-91-8)
- 2-(Dimethylamino)-3-methylbenzaldehyde (CAS 87067-13-8)
- 1-Methyladamantane (CAS 768-91-2)
- 3-(3-Chloro-2-fluorophenyl)propanoic acid (CAS 886498-12-0)
- 5-(Oxiran-2-ylmethyl)benzo[d][1,3]dioxole (CAS 7470-44-2)
- Posaconazole Impurity 131 (CAS CATO-C4X-1208131)
- (R)-2-((tert-butoxycarbonyl)amino)hex-5-enoic acid (CAS 219819-76-8)
- (2E)-1-{[1,1'-Biphenyl]-4-yl}-3-(furan-2-yl)prop-2-en-1-one (CAS 132434-51-6)
- Semaglutide (CAS 910463-68-2)
Why CATO?
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