Posaconazole Impurity 131 CAS CATO-C4X-1208131
| CAS No. | CATO-C4X-1208131 |
| Molecular Formula | C14H16FIO3 |
| Molecular Weight | 378.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Posaconazole Impurity 131 (C14H16FIO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Posaconazole Impurity 131 (CAS CATO-C4X-1208131) is a certified pharmaceutical impurity reference standard with the molecular formula C14H16FIO3 and a molecular weight of 378.18 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Posaconazole Impurity 131 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H16FIO3 |
| Molecular Weight | 378.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
Related Posaconazole Standards
- Posaconazole Impurity 72 (CAS CATO-C4X-120872)
- Posaconazole Impurity 73 (CAS CATO-C4X-120873)
- Posaconazole impurity 218 (CAS CATO-C4X-1208218)
- Posaconazole Impurity 66 (CAS 165115-83-3)
- Posaconazole impurity 248 (CAS CATO-C4X-1208248)
- Posaconazole Impurity 135 (CAS CATO-C4X-1208135)
- Posaconazole Impurity 126 (CAS 208187-15-9)
- Posaconazole Impurity 56 (CAS 184177-81-9)
Recommended Standards
- 4-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)benzamide (CAS 338409-32-8)
- (2E)-3-(6-Bromo-2H-1,3-benzodioxol-5-yl)-N-[(4-fluorophenyl)methyl]prop-2-enamide (CAS 1164529-57-0)
- 3-Chloro-6-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}pyridazine (CAS 303149-98-6)
- 2-(4-(Benzyloxy)-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1218790-07-8)
- Tenofovir disoproxil Impurity 104 (CAS CATO-C4X-1076104)
- Avanafil Impurity 41 (CAS CATO-C4X-1118141)
- Methyl Salicylate EP Impurity L (CAS 33528-09-5)
- 3-([1,1'-Biphenyl]-4-yloxy)azetidine (CAS 227304-96-3)
- 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4,6-dipentylphenol (CAS 21615-49-6)
- 3-Chloro-N-(1,1-dimethylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-benzamide (CAS 1442432-30-5)
- 5-(Trifluoromethyl)furan-2-carbonitrile (CAS 65865-27-2)
- 2,4-Dichloro-6-(methylsulfanyl)-5-nitropyrimidine (CAS 1451885-60-1)
- 4-(Aminomethyl)pyrrolidin-3-one O-methyl oxime (CAS 175463-84-0)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com