Sertraline EP Impurity B HCl CAS 52758-05-1
| CAS No. | 52758-05-1 |
| Molecular Formula | C17H19N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Sertraline EP Impurity B HCl (CAS 52758-05-1), a pharmacopoeial impurity reference standard (molecular formula C17H19NHCl, MW 273.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C17H19NHCl, Sertraline EP Impurity B HCl contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 273.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H19N HCl |
| Molecular Weight | 273.80 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- Sertraline Acetamide (CAS 1097616-52-8)
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- Sertraline Impurity 26 (CAS 1198115-10-4（free base）)
- Sertraline RC 11 (CAS 1217630-23-3)
- Sertraline-d3 Hydrochloride (CAS 1217741-83-7)
- Sertraline Impurity 50 HCl (CAS 122873-20-5 (free base))
- Sertraline EP Impurity F Enantiomer (CAS 124379-29-9)
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- 1-(2,4-Dichlorophenyl)pentan-2-one (CAS 1175706-65-6)
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- (E)-4-(3-(2-Hydroxyphenyl)-3-oxoprop-1-en-1-yl)benzoic acid (CAS 919092-43-6)
- Endo-Ala35-Tirzepatide (CAS CATO-CPTD788687)
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