3-(4-Bromophenyl)-6-fluoro-4-methylcoumarin CAS 527751-41-3

Purity 97%+In StockPharmaceutical Standards
CAS No.527751-41-3
Molecular FormulaC16H10BrFO2
Molecular Weight333.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Bromophenyl)-6-fluoro-4-methylcoumarin CAS 527751-41-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Bromophenyl)-6-fluoro-4-methylcoumarin.

3-(4-Bromophenyl)-6-fluoro-4-methylcoumarin (CAS 527751-41-3) is a high-purity analytical reference standard with the molecular formula C16H10BrFO2 and a molecular weight of 333.15 g/mol.

Structurally, 3-(4-Bromophenyl)-6-fluoro-4-methylcoumarin (C16H10BrFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 333.15 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-(4-Bromophenyl)-6-fluoro-4-methylcoumarin under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H10BrFO2
Molecular Weight333.15 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Br-containing

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